Last data update: Apr 29, 2024. (Total: 46658 publications since 2009)
Records 1-18 (of 18 Records) |
Query Trace: Bancroft E[original query] |
---|
Deaths of U.S. citizens undergoing cosmetic surgery - Dominican Republic, 2009-2022
Hudson M , Matos JA , Alvarez B , Safstrom J , Torres F , Premjee S , Bonilla L , Park B , Bancroft E , Garcia M . MMWR Morb Mortal Wkly Rep 2024 73 (3) 62-65 Although infections resulting from cosmetic surgery performed outside the United States have been regularly reported, deaths have rarely been identified. During 2009-2022, 93 U.S. citizens died after receiving cosmetic surgery in the Dominican Republic. The number of deaths increased from a mean of 4.1 per year during 2009-2018 to a mean of 13.0 during 2019-2022 with a peak in of 17 in 2020. A subset of post-cosmetic surgery deaths occurring during peak years was investigated, and most deaths were found to be the result of embolic events (fat emboli or venous thromboembolism) for which a high proportion of the patients who died had risk factors, including obesity and having multiple procedures performed during the same operation. These risk factors might have been mitigated or prevented with improved surgical protocols and postoperative medical care, including prophylactic measures against venous thromboembolism. U.S. citizens interested in receiving elective cosmetic surgery outside the United States should consult with their health care professionals regarding their risk for adverse outcomes. Public health authorities can support provider education on the importance of preoperative patient evaluation and the potential danger of performing multiple cosmetic procedures in one operation. |
Infection Prevention and Control Initiatives to Prevent Healthcare-Associated Transmission of SARS-CoV-2, East Africa
Gomes DJ , Hazim C , Safstrom J , Herzig C , Luvsansharav U , Dennison C , Ahmed Y , Wesangula E , Hokororo J , Amone J , Tekle B , Owiso G , Mutayoba R , Lamorde M , Akello E , Kassa G , Feleke B , Ndegwa L , Kazaura K , Musisi D , Date A , Park BJ , Bancroft E . Emerg Infect Dis 2022 28 (13) S255-s261 The coronavirus disease pandemic has highlighted the need to establish and maintain strong infection prevention and control (IPC) practices, not only to prevent healthcare-associated transmission of SARS-CoV-2 to healthcare workers and patients but also to prevent disruptions of essential healthcare services. In East Africa, where basic IPC capacity in healthcare facilities is limited, the US Centers for Disease Control and Prevention (CDC) supported rapid IPC capacity building in healthcare facilities in 4 target countries: Tanzania, Ethiopia, Kenya, and Uganda. CDC supported IPC capacity-building initiatives at the healthcare facility and national levels according to each country's specific needs, priorities, available resources, and existing IPC capacity and systems. In addition, CDC established a multicountry learning network to strengthen hospital level IPC, with an emphasis on peer-to-peer learning. We present an overview of the key strategies used to strengthen IPC in these countries and lessons learned from implementation. |
Bi-national Outbreak of Salmonella Newport Infections Linked to Onions: the United States Experience.
McCormic ZD , Patel K , Higa J , Bancroft J , Donovan D , Edwards L , Cheng J , Adcock B , Bond C , Pereira E , Doyle M , Wise ME , Gieraltowski L . Epidemiol Infect 2022 150 1-23 From 2016-2019, dry bulb onions were the suspected cause of three multistate outbreaks in the United States. We investigated a large multistate outbreak of Salmonella Newport infections that caused illnesses in both the United States and Canada in 2020. Epidemiologic, laboratory and traceback investigations were conducted to determine the source of the infections, and data were shared among U.S. and Canadian public health officials. We identified 1127 U.S. illnesses from 48 states with illness onset dates ranging from 19 June to 11 September 2020. Sixty-six per cent of ill people reported consuming red onions in the week before illness onset. Thirty-five illness sub-clusters were identified during the investigation and seventy-four per cent of sub-clusters served red onions to customers during the exposure period. Traceback for the source of onions in illness sub-clusters identified a common onion grower in Bakersfield, CA as the source of red onions, and onions were recalled at this time. Although other strains of Salmonella Newport were identified in environmental samples collected at the Bakersfield, CA grower, extensive environmental and product testing did not yield the outbreak strain. This was the third largest U.S. foodborne Salmonella outbreak in the last 30 years. It is the first U.S. multistate outbreak with a confirmed link to dry bulb onions, and it was nearly 10-fold larger than prior outbreaks with a suspected link to onions. This outbreak is notable for its size and scope, as well as the international data sharing that led to implication of red onions as the primary cause of the outbreak. Although an environmental assessment at the grower identified several factors that likely contributed to the outbreak, no main reason was identified. The expedient identification of the outbreak vehicle and response of multiple public health agencies allowed for recall and removal of product from the marketplace, and rapid messaging to both the public and industry on actions to protect consumers; these features contributed to a decrease in cases and expeditious conclusion of the outbreak. |
Improving hand hygiene practices in two regional hospitals in Kenya using a continuous quality improvement (CQI) approach
Kibira J , Kihungi L , Ndinda M , Wesangula E , Mwangi C , Muthoni F , Augusto O , Owiso G , Ndegwa L , Luvsansharav UO , Bancroft E , Rabinowitz P , Lynch J , Njoroge A . Antimicrob Resist Infect Control 2022 11 (1) 56 BACKGROUND: Hand hygiene (HH) is central in prevention of health care-associated infections. In low resource settings, models to improve HH compliance are needed. We implemented a continuous quality improvement (CQI) program targeting HH in two hospitals in Kenya. OBJECTIVE: To determine the impact of the HH CQI program and identify factors associated with HH compliance between 2018 and 2019. METHODS: A CQI project targeting the improvement of hand hygiene was implemented, including training and mentorship. Data were collected monthly between April 2018 and December 2019 in Thika and Kitale Hospitals. Healthcare workers trained on Infection Prevention and Control (IPC) observed and recorded HH opportunities and subsequent compliance among staff, including nurses, clinicians, and auxiliary staff, using the World Health Organization's "My Five Moments for Hand Hygiene" tool. Covariates were explored using mixed-effects logistic regression with random department-level intercepts. RESULTS: Hand hygiene compliance improved from 27% at baseline to 44% after 21 months. Indication/moment for HH was significantly associated with compliance. Adjusting for site, professional category and department, compliance was higher after a moment of body fluid exposure (aOR 1.43, 95% CI 1.17-1.74, p value < 0.001) and lower before an aseptic procedure (aOR 0.12, 95% CI 0.08-0.17, p value < 0.001) compared to after patient contact. Wearing of gloves often replaced proper HH in surgical departments, which although not significant, had lower compliance compared to departments for internal medicine (aOR 0.93, 95% CI 0.85-1.02). Adjusted HH compliance from all quarters improved from baseline, but comparing each quarter to the previous quarter, the improvement fluctuated over time. CONCLUSION: Training and mentorship on the importance of HH for all moments is needed to improve overall HH compliance. CQI with regular monitoring and feedback of HH performance can be an effective approach in improving HH compliance in public hospitals in Kenya. |
Widespread sharing of pneumococcal strains in a rural African setting: proximate villages are more likely to share similar strains that are carried at multiple timepoints.
Senghore M , Chaguza C , Bojang E , Tientcheu PE , Bancroft RE , Lo SW , Gladstone RA , McGee L , Worwui A , Foster-Nyarko E , Ceesay F , Okoi CB , Klugman KP , Breiman RF , Bentley SD , Adegbola R , Antonio M , Hanage WP , Kwambana-Adams BA . Microb Genom 2022 8 (2) The transmission dynamics of Streptococcus pneumoniae in sub-Saharan Africa are poorly understood due to a lack of adequate epidemiological and genomic data. Here we leverage a longitudinal cohort from 21 neighbouring villages in rural Africa to study how closely related strains of S. pneumoniae are shared among infants. We analysed 1074 pneumococcal genomes isolated from 102 infants from 21 villages. Strains were designated for unique serotype and sequence-type combinations, and we arbitrarily defined strain sharing where the pairwise genetic distance between strains could be accounted for by the mean within host intra-strain diversity. We used non-parametric statistical tests to assess the role of spatial distance and prolonged carriage on strain sharing using a logistic regression model. We recorded 458 carriage episodes including 318 (69.4 %) where the carried strain was shared with at least one other infant. The odds of strain sharing varied significantly across villages (χ(2)=47.5, df=21, P-value <0.001). Infants in close proximity to each other were more likely to be involved in strain sharing, but we also show a considerable amount of strain sharing across longer distances. Close geographic proximity (<5 km) between shared strains was associated with a significantly lower pairwise SNP distance compared to strains shared over longer distances (P-value <0.005). Sustained carriage of a shared strain among the infants was significantly more likely to occur if they resided in villages within a 5 km radius of each other (P-value <0.005, OR 3.7). Conversely, where both infants were transiently colonized by the shared strain, they were more likely to reside in villages separated by over 15 km (P-value <0.05, OR 1.5). PCV7 serotypes were rare (13.5 %) and were significantly less likely to be shared (P-value <0.001, OR -1.07). Strain sharing was more likely to occur over short geographical distances, especially where accompanied by sustained colonization. Our results show that strain sharing is a useful proxy for studying transmission dynamics in an under-sampled population with limited genomic data. This article contains data hosted by Microreact. |
Standardizing clinical culture specimen collection in Ethiopia: a training-of-trainers
Kue J , Bersani A , Stevenson K , Yimer G , Wang SH , Gebreyes W , Hazim C , Westercamp M , Omondi M , Amare B , Alebachew G , Abubeker R , Fentaw S , Tigabu E , Kirley D , Vanderende D , Bancroft E , Gallagher KM , Kanter T , Balada-Llasat JM . BMC Med Educ 2021 21 (1) 195 BACKGROUND: Proper specimen collection is central to improving patient care by ensuring optimal yield of diagnostic tests, guiding appropriate management, and targeting treatment. The purpose of this article is to describe the development and implementation of a training-of-trainers educational program designed to improve clinical culture specimen collection among healthcare personnel (HCP) in Ethiopia. METHODS: A Clinical Specimen Collection training package was created consisting of a Trainer's Manual, Reference Manual, Assessment Tools, Step-by-Step Instruction Guides (i.e., job aides), and Core Module PowerPoint Slides. RESULTS: A two-day course was used in training 16 master trainers and 47 facility-based trainers responsible for cascading trainings on clinical specimen collection to HCP at the pre-service, in-service, or national-levels. The Clinical Specimen Collection Package is offered online via The Ohio State University's CANVAS online platform. CONCLUSIONS: The training-of-trainers approach may be an effective model for development of enhanced specimen collection practices in low-resource countries. |
Carriage Dynamics of Pneumococcal Serotypes in Naturally Colonized Infants in a Rural African Setting During the First Year of Life.
Chaguza C , Senghore M , Bojang E , Lo SW , Ebruke C , Gladstone RA , Tientcheu PE , Bancroft RE , Worwui A , Foster-Nyarko E , Ceesay F , Okoi C , McGee L , Klugman KP , Breiman RF , Barer MR , Adegbola RA , Antonio M , Bentley SD , Kwambana-Adams BA . Front Pediatr 2020 8 587730 Streptococcus pneumoniae (the pneumococcus) carriage precedes invasive disease and influences population-wide strain dynamics, but limited data exist on temporal carriage patterns of serotypes due to the prohibitive costs of longitudinal studies. Here, we report carriage prevalence, clearance and acquisition rates of pneumococcal serotypes sampled from newborn infants bi-weekly from weeks 1 to 27, and then bi-monthly from weeks 35 to 52 in the Gambia. We used sweep latex agglutination and whole genome sequencing to serotype the isolates. We show rapid pneumococcal acquisition with nearly 31% of the infants colonized by the end of first week after birth and quickly exceeding 95% after 2 months. Co-colonization with multiple serotypes was consistently observed in over 40% of the infants at each sampling point during the first year of life. Overall, the mean acquisition time and carriage duration regardless of serotype was 38 and 24 days, respectively, but varied considerably between serotypes comparable to observations from other regions. Our data will inform disease prevention and control measures including providing baseline data for parameterising infectious disease mathematical models including those assessing the impact of clinical interventions such as pneumococcal conjugate vaccines. |
Task shifting for initiation and monitoring of antiretroviral therapy for HIV-infected adults in Uganda: The SHARE Trial
Sekiziyivu AB , Bancroft E , Rodriguez EM , Sendagala S , Muniina PN , Sserunga MN , Kiragga NA , Musaazi J , Musinguzi J , Sande E , Bartholow B , Dalal S , Tusiime JB , Kambugu A . J Acquir Immune Defic Syndr 2020 86 (3) e71-e79 BACKGROUND: With countries moving towards the World Health Organization's "Treat All" recommendation, there is need to initiate more HIV-infected persons on antiretroviral therapy (ART). In resource-limited settings, task shifting is one approach that can address clinician shortages. SETTING: Uganda METHODS:: We conducted a randomized controlled trial to test if nurse-initiated and monitored antiretroviral therapy (NIMART) is non-inferior to clinician-initiated and monitored ART (CIMART) in HIV-infected adults in Uganda. Study participants were HIV-infected, ART-naïve, and clinically stable adults. The primary outcome was a composite endpoint of any of the following: all-cause mortality, virological failure, toxicity, and loss to follow up at 12 months post-ART initiation. RESULTS: Over half of the study cohort (1,760) was female (54.9%). The mean age was 35.1 years (standard deviation 9.51). Five hundred and thirty-three (31.6%) participants experienced the composite endpoint. At 12 months post-ART initiation, NIMART was non-inferior to CIMART. The intention-to-treat site-adjusted risk differences for the composite endpoint were -4.1 (97.5% CI = -9.8 to 0.2) with complete case analysis (CCA) and -3.4 (97.5% CI = -9.1 to 2.5) with multiple imputation analysis (MIA). Per-protocol site-adjusted risk differences were -3.6 (97.5% CI = -10.5 to 0.6) for CCA and -3.1 (-8.8 to 2.8) for MIA. This difference was within hypothesized margins (6%) for non-inferiority. CONCLUSIONS: Nurses were non-inferior to clinicians for initiation and monitoring of ART. Task shifting to trained nurses is a viable means to increase access to ART. Future studies should evaluate NIMART for other groups (e.g., children, adolescents, and unstable patients). |
Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation.
Chaguza C , Senghore M , Bojang E , Gladstone RA , Lo SW , Tientcheu PE , Bancroft RE , Worwui A , Foster-Nyarko E , Ceesay F , Okoi C , McGee L , Klugman KP , Breiman RF , Barer MR , Adegbola RA , Antonio M , Bentley SD , Kwambana-Adams BA . Nat Commun 2020 11 (1) 3442 Genomic evolution, transmission and pathogenesis of Streptococcus pneumoniae, an opportunistic human-adapted pathogen, is driven principally by nasopharyngeal carriage. However, little is known about genomic changes during natural colonisation. Here, we use whole-genome sequencing to investigate within-host microevolution of naturally carried pneumococci in ninety-eight infants intensively sampled sequentially from birth until twelve months in a high-carriage African setting. We show that neutral evolution and nucleotide substitution rates up to forty-fold faster than observed over longer timescales in S. pneumoniae and other bacteria drives high within-host pneumococcal genetic diversity. Highly divergent co-existing strain variants emerge during colonisation episodes through real-time intra-host homologous recombination while the rest are co-transmitted or acquired independently during multiple colonisation episodes. Genic and intergenic parallel evolution occur particularly in antibiotic resistance, immune evasion and epithelial adhesion genes. Our findings suggest that within-host microevolution is rapid and adaptive during natural colonisation. |
Status of HIV epidemic control among adolescent girls and young women aged 15-24 years - seven African countries, 2015-2017
Brown K , Williams DB , Kinchen S , Saito S , Radin E , Patel H , Low A , Delgado S , Mugurungi O , Musuka G , Tippett Barr BA , Nwankwo-Igomu EA , Ruangtragool L , Hakim AJ , Kalua T , Nyirenda R , Chipungu G , Auld A , Kim E , Payne D , Wadonda-Kabondo N , West C , Brennan E , Deutsch B , Worku A , Jonnalagadda S , Mulenga LB , Dzekedzeke K , Barradas DT , Cai H , Gupta S , Kamocha S , Riggs MA , Sachathep K , Kirungi W , Musinguzi J , Opio A , Biraro S , Bancroft E , Galbraith J , Kiyingi H , Farahani M , Hladik W , Nyangoma E , Ginindza C , Masangane Z , Mhlanga F , Mnisi Z , Munyaradzi P , Zwane A , Burke S , Kayigamba FB , Nuwagaba-Biribonwoha H , Sahabo R , Ao TT , Draghi C , Ryan C , Philip NM , Mosha F , Mulokozi A , Ntigiti P , Ramadhani AA , Somi GR , Makafu C , Mugisha V , Zelothe J , Lavilla K , Lowrance DW , Mdodo R , Gummerson E , Stupp P , Thin K , Frederix K , Davia S , Schwitters AM , McCracken SD , Duong YT , Hoos D , Parekh B , Justman JE , Voetsch AC . MMWR Morb Mortal Wkly Rep 2018 67 (1) 29-32 In 2016, an estimated 1.5 million females aged 15-24 years were living with human immunodeficiency virus (HIV) infection in Eastern and Southern Africa, where the prevalence of HIV infection among adolescent girls and young women (3.4%) is more than double that for males in the same age range (1.6%) (1). Progress was assessed toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) 2020 targets for adolescent girls and young women in sub-Saharan Africa (90% of those with HIV infection aware of their status, 90% of HIV-infected persons aware of their status on antiretroviral treatment [ART], and 90% of those on treatment virally suppressed [HIV viral load <1,000 HIV RNA copies/mL]) (2) using data from recent Population-based HIV Impact Assessment (PHIA) surveys in seven countries. The national prevalence of HIV infection in adolescent girls and young women aged 15-24 years, the percentage who were aware of their status, and among those persons who were aware, the percentage who had achieved viral suppression were calculated. The target for viral suppression among all persons with HIV infection is 73% (the product of 90% x 90% x 90%). Among all seven countries, the prevalence of HIV infection among adolescent girls and young women was 3.6%; among those in this group, 46.3% reported being aware of their HIV-positive status, and 45.0% were virally suppressed. Sustained efforts by national HIV and public health programs to diagnose HIV infection in adolescent girls and young women as early as possible to ensure rapid initiation of ART should help achieve epidemic control among adolescent girls and young women. |
Case finding using syndromic surveillance data during an outbreak of Shiga toxin-producing Escherichia coli O26 infections, Oregon, 2015
Hines JZ , Bancroft J , Powell M , Hedberg K . Public Health Rep 2017 132 (4) 33354917708994 Shiga toxin-producing Escherichia coli (STEC) causes an estimated 265 000 infections in the United States annually. Of emerging non-O157:H7 STEC serotypes, O26 is the most commonly recognized. During an outbreak of STEC O26 in Oregon in 2015, we used syndromic surveillance data to supplement case finding by laboratory reporting. From 157 records retrieved by querying syndromic surveillance data, we detected 4 confirmed and 5 suspected cases. However, none of the suspected cases were confirmed by stool culture, and by the time that the data were being analyzed, the confirmed cases were already known to investigators. Syndromic surveillance data can potentially supplement case finding during outbreaks of foodborne disease. To be an effective case-finding strategy, timely completion of all steps, including collecting specimens from suspected cases, should be performed in real time. |
Incidence of crohn's disease and ulcerative colitis in Rhode Island: Report from the Ocean State Crohn's and Colitis Area Registry
Shapiro JM , Zoega H , Shah SA , Bright RM , Mallette M , Moniz H , Grabert SA , Bancroft B , Merrick M , Flowers NT , Samad Z , Lidofsky S , LeLeiko NS , Sands BE . Inflamm Bowel Dis 2016 22 (6) 1456-61 BACKGROUND: Studies describing the incidence of Crohn's disease (CD) and ulcerative colitis (UC) are uncommon in the United States. We sought to determine the incidence of CD and UC in the state of Rhode Island. METHODS: The Ocean State Crohn's and Colitis Area Registry is a state-based inception cohort of patients newly diagnosed with inflammatory bowel disease (IBD) in Rhode Island. To confirm a diagnosis of CD, UC, or IBD unclassified (IBDU), the National Institute of Diabetes and Digestive and Kidney Diseases IBD Genetics Consortium criteria were applied in a review of medical records from gastroenterology practices located in the state of Rhode Island and adjacent to the Rhode Island border in Massachusetts and Connecticut. Using population-based data, we determined the statewide incidence of IBD in Rhode Island from 2008 to 2010. RESULTS: A total of 971 Rhode Island residents were diagnosed with IBD, including 444 with CD, 486 with UC, and 41 with IBD unclassified from 2008 to 2010. The overall age- and sex-adjusted IBD incidence was 30.2 (95% confidence interval, 28.3-32.1) per 100,000 persons in this time frame with 13.9, 15.1, and 1.3 per 100,000 diagnosed with CD, UC, and IBD unclassified, respectively. Of the total incident cases in Rhode Island, 30% (n = 291) were enrolled in Ocean State Crohn's and Colitis Area Registry for follow-up. CONCLUSIONS: The incidence of IBD in Rhode Island is higher than that previously reported by other population-based cohorts in the United States. Prospective follow-up of individuals enrolled in the community-based Ocean State Crohn's and Colitis Area Registry cohort is ongoing. |
Health care-associated infection outbreak investigations in outpatient settings, Los Angeles County, California, USA, 2000-2012
OYong K , Coelho L , Bancroft E , Terashita D . Emerg Infect Dis 2015 21 (8) 1317-21 Health care services are increasingly delivered in outpatient settings. However, infection control oversight in outpatient settings to ensure patient safety has not improved and literature quantifying reported health care-associated infection outbreaks in outpatient settings is scarce. The objective of this analysis was to characterize investigations of suspected and confirmed outbreaks in outpatient settings in Los Angeles County, California, USA, reported during 2000-2012, by using internal logs; publications; records; and correspondence of outbreak investigations by characteristics of the setting, number, and type of infection control breaches found during investigations, outcomes of cases, and public health responses. Twenty-eight investigations met the inclusion criteria. Investigations occurred frequently, in diverse settings, and required substantial public health resources. Most outpatient settings investigated had >1 infection control breach. Lapses in infection control were suspected to be the outbreak source for 16 of the reviewed investigations. |
Infection prevention and control in the podiatric medical setting: challenges to providing consistently safe care
Wise ME , Bancroft E , Clement EJ , Hathaway S , High P , Kim M , Lutterloh E , Perz JF , Sehulster LM , Tyson C , White-Comstock MB , Montana B . J Am Podiatr Med Assoc 2015 Unsafe practices are an underestimated contributor to the disease burden of bloodborne viruses. Outbreaks associated with failures in basic infection prevention have been identified in nonhospital settings with increased frequency in the United States during the past 15 years, representing an alarming trend and indicating that the challenge of providing consistently safe care is not always met. As has been the case with most medical specialties, there have been public health investigations by state and local health departments, and the Centers for Disease Control and Prevention have identified some instances of unsafe practices that have placed podiatric medical patients at risk for viral, bacterial, and fungal infections. All health-care providers, including podiatric physicians, must make infection prevention a priority in any setting in which care is delivered. |
Viruses associated with acute respiratory infections and influenza-like illness among outpatients from the Influenza Incidence Surveillance Project, 2010-2011
Fowlkes A , Giorgi A , Erdman D , Temte J , Goodin K , Di Lonardo S , Sun Y , Martin K , Feist M , Linz R , Boulton R , Bancroft E , McHugh L , Lojo J , Filbert K , Finelli L . J Infect Dis 2013 209 (11) 1715-25 BACKGROUND: The Influenza Incidence Surveillance Project (IISP) monitored outpatient acute respiratory infection (ARI) and influenza like illness (ILI) to determine the incidence and contribution of associated viral etiologies. METHODS: From August 2010 through July 2011, 57 outpatient healthcare providers with enumerated patient populations in 12 US sites reported weekly the number of ILI and ARI (> 2 respiratory symptoms not meeting ILI criteria) visits and collected respiratory specimens on a subset for viral testing. Incidence was estimated using number of patients in the practice as the denominator, and virus-specific incidence was extrapolated from the proportion of patients testing positive. RESULTS: The age-adjusted annual incidence of outpatient visits for ARI and ILI combined was 95/1,000 population, with a viral etiology identified in 58% of specimens. Most frequently detected were rhinoviruses/enteroviruses (RV/EV) and influenza (21% each), resulting in an extrapolated incidence of 20 and 19/1,000 population, respectively. The influenza incidence was highest among patients aged 2 to 17 years, while other viruses had varied patterns among age groups. CONCLUSIONS: The IISP provides a unique opportunity to estimate outpatient respiratory illness burden by etiology. Influenza and RV/EV infections represent a substantial burden of respiratory disease in the US outpatient setting, particularly among children. |
Outbreak of acute hepatitis B virus infections associated with podiatric care at a psychiatric long-term care facility
Wise ME , Marquez P , Sharapov U , Hathaway S , Katz K , Tolan S , Beaton A , Drobeniuc J , Khudyakov Y , Hu DJ , Perz J , Thompson ND , Bancroft E . Am J Infect Control 2011 40 (1) 16-21 BACKGROUND: Effective measures exist to prevent health care-associated hepatitis B virus (HBV) transmission, yet outbreaks continue to occur. In 2008, the Los Angeles County Department of Public Health identified an outbreak of HBV infections among psychiatric long-term care facility residents. METHODS: Residents underwent HBV serologic testing and were classified as acutely infected, chronically infected, susceptible, or immune. Persons residing in the facility during 2008 were enrolled in a retrospective cohort study to identify risk factors for acute HBV infection. We assessed infection control practices at the facility. RESULTS: Nine of 81 residents (11%) enrolled in the cohort study had acute HBV infection. Five of 15 residents (33%) undergoing podiatric care on a single day subsequently developed acute infection (rate ratio, 4.33; 95% confidence interval, 1.18-15.92). Infection control observations of the consulting podiatrist revealed opportunities for cross-contamination of instruments with blood. Other potential health care and behavioral modes of transmission were identified as well. Residents were offered HBV vaccination, and infection control recommendations were implemented by the podiatrist and facility. CONCLUSIONS: Of the multiple potential transmission modes identified, exposure to HBV during podiatry was likely the dominant mode in this outbreak. Long-term care facilities should ensure compliance with infection control standards among staff and consulting health care providers. |
Comparison of survey methods in norovirus outbreak investigation, Oregon, USA, 2009
Oh JY , Bancroft JE , Cunningham MC , Keene WE , Lyss SB , Cieslak PR , Hedberg K . Emerg Infect Dis 2010 16 (11) 1773-6 We compared data from an Internet-based survey and a telephone-based survey during a 2009 norovirus outbreak in Oregon. Survey initiation, timeliness of response, and attack rates were comparable, but participants were less likely to complete Internet questions. Internet-based surveys permit efficient data collection but should be designed to maximize complete responses. |
Hospitalization of paediatric patients for methicillin-resistant Staphylococcus aureus skin and soft-tissue infection, 1998-2006
Sircar KD , Bancroft E , Nguyen DM , Mascola L . Epidemiol Infect 2010 138 (5) 677-82 Hospital discharge reports have provided data for studies of methicillin-resistant Staphylococcus aureus (MRSA) skin and soft-tissue infection (SSTI) studies. This analysis determined the sensitivity and positive predictive value of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) code combinations to calculate hospitalization incidence rates, representativeness of a set of three ICD-9-CM codes to define MRSA SSTI, and hospitalization incidence rate trends for paediatric MRSA SSTIs in Los Angeles County (LAC). Using 133 cases from 31 hospitals, we found that the set of three ICD-9-CM codes used to define laboratory-confirmed cases had one of the highest positive predictive values (49%). There was no difference in age and race between those categorized using three codes vs. other code combinations. A dramatic increase in paediatric MRSA SSTI cases occurred in LAC during 1998-2006. We conclude that this combination of codes may be used to determine the rise of MRSA SSTIs in paediatric populations. |
- Page last reviewed:Feb 1, 2024
- Page last updated:Apr 29, 2024
- Content source:
- Powered by CDC PHGKB Infrastructure